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Researchers Conclude Suicide Warning On Antidepressant Labels Is Justified

Researchers examining the validity of the black box warning on antidepressants have concluded that the warning of the increased risk of suicidal thoughts and actions in children and young adults is clearly justified.

The best evidence available from clinical trials “demonstrated increased risk of suicidality adverse events among youth taking antidepressants,” according to researchers from universities in the United States and Australia, whose findings were published in the journal Frontiers in Psychiatry.

The researchers also examined critics’ claims that the black-box warning led to fewer prescriptions for antidepressants and, as a result, higher rates of suicide and suicide attempts.

Instead, researchers found that the rise in suicidal behavior in children and young adults occurred while prescriptions for antidepressants also increased.

“More recent data suggest that increasing antidepressant prescriptions are related to more youth suicide attempts and more completed suicides among American children and adolescents,” the researchers wrote.

“The black box warning is firmly rooted in solid data, whereas attempts to claim the warning has caused harm are based on quite weak evidence,” they concluded.

A black box warning on a drug label is one of the FDA’s strongest warnings, reserved for drugs that carry significant risk of serious or fatal side effects.

The black box warning on antidepressants was first required by the FDA in 2004 to warn of the increased risk of suicidal thoughts and actions in children and adolescents.  The warning was expanded in 2007 to include young adults.

“When a clear body of evidence points to increased treatment-linked risk, patients and healthcare providers should be made aware of these risks,” the researchers wrote, noting their duty to warn.

WARNING: Anyone wishing to discontinue or change the dose of a psychiatric drug is cautioned to do so only under the supervision of a competent medical doctor because of potentially dangerous, even life-threatening mental and physical withdrawal symptoms.

If you or someone you know has experienced harmful side effects from antidepressants, we want to talk with you.  You can contact us by clicking here or by calling 303-789-5225.  All information will be kept in the strictest confidence.

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News for Colorado

Remember What Unleashed The Hatred Of The Aurora Theater Shooter

On the occasion of today’s 5-year remembrance of the July 20, 2012 mass shooting at an Aurora movie theater that killed 12 people and wounded 70 others, remember the chilling words of the shooter which foreshadowed the massacre: “Hatred unchecked,” “no fear of consequences.”

Then consider the events that led up to shooter James Holmes writing these ominous words in a personal notebook.

Holmes, a graduate student at the University of Colorado, contacted the campus mental health center for help with his obsessive thoughts of killing people and his anxiety in social situations.

The psychiatrist who met with him immediately prescribed psychiatric drugs linked to aggression, violence and homicide, including the SSRI antidepressant Zoloft.

Within weeks, Holmes had written an alarming series of statements in the notebook where he recorded his thoughts during his psychiatric treatment:  “First appearance of mania occurs, not good mania.  Anxiety and fear disappears.  No more fear….  No fear of consequences…  No more fear, hatred unchecked.”

Peter Breggin, M.D., a Harvard-trained psychiatrist who has been involved as an expert with a number of cases of mass murder, has written that “exposing Holmes to Zoloft was like pouring gasoline on a fire.”

Breggin says Holmes was on Zoloft for about 94 days before abruptly stopping around June 30, just 20 days before his deadly rampage.

“An abrupt withdrawal might have worsened his condition, but the main contributing factor to the violence was his lengthy exposure to a drug that worsened his condition and drove him into psychosis,” he writes.  “He had a manic-like psychosis while taking the Zoloft and this would not have abated for some time after stopping the medication.”

Breggin’s conclusion: “I have no doubt that Zoloft contributed to Holmes’ escalating violence and that without it he probably would not have committed mass murder.”

At least 34 research studies and 26 warnings issued by international drug regulatory authorities have warned about the dangers of SSRI antidepressants like Zoloft.

Zoloft is also on the list of the prescription drugs most associated with the incidents of violence that have been reported to the FDA, according to a 2010 study in the Public Library of Science ONE.

Only by fully investigating psychiatric drugs’ known links to violence and homicide can we hope to prevent such tragic bloodshed in the future.

Warning: Anyone wishing to discontinue an antidepressant or any other psychiatric drug is cautioned to do so only under the supervision of a competent medical doctor because of potentially dangerous withdrawal symptoms.

If you or someone you know has become violent from taking an SSRI antidepressant or any other psychiatric drug, please report it to the FDA by clicking here.  And we want to talk to you about your experience.  You can contact us privately by clicking here or by calling 303-789-5225.  All information will be kept in the strictest confidence.

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General News News for Colorado

Aurora Theater Shooter Felt Mania and Hatred After Taking Psychiatric Drugs Linked To Violence

The first time they met, the psychiatrist who treated Aurora theater shooter James Holmes prescribed him psychiatric drugs linked to violence and homicide, even though Holmes openly admitted he was obsessively having thoughts of killing people.

In fact, Holmes told the psychiatrist that his homicidal thoughts “were the worst they had been.”

Some time after taking the psychiatric drugs, Holmes writes in a notebook that the “first appearance of mania” occurs, that he has “no fear of consequences,” and that his “hatred [is] unchecked.”

Holmes is currently standing trial on charges related to his killing 12 people and injuring 70 others in an attack on the Aurora Century 16 movie theater during a packed, midnight screening of the film “The Dark Knight Rises” on July 19, 2012.

Holmes was a graduate student in the neuroscience program at the University of Colorado when he contacted the Student Mental Health Center for help with his obsessive thoughts of killing people and his anxiety in social situations.  He was referred to psychiatrist Lynne Fenton for treatment.  He met with Fenton five times in the final months before he dropped out of school.  He went on his deadly rampage a few weeks later.

In a notebook where Holmes recorded his thoughts during the time he was meeting with Fenton, he noted that at their first meeting, Fenton “immediately prescribed antidepressants.”  The notebook entry went on to report that the drugs were ineffective: “No effect when needed.”

This is followed by a chilling series of statements:  “First appearance of mania occurs, not good mania.  Anxiety and fear disappears.  No more fear….  No fear of consequences…  No more fear, hatred unchecked.”

Meds psychiatrist prescribed are on list of drugs most associated with violence

According to Fenton’s court testimony, Holmes told her at their first meeting about his obsessive thoughts about killing people.  He used the psychiatric term “OCD” (obsessive compulsive disorder) to describe the recurring thoughts.

Fenton testified about Holmes having these homicidal thoughts (“ideation”): “He said that his OCD symptoms – and that was referring to his thoughts of homicidal ideation – were the worst they had been.”

Fenton prescribed the psychiatric drugs sertraline and clonazepam to Holmes for his anxiety at that first meeting.

Both drugs are on the list of prescription drugs most associated with incidents of violence reported to the FDA, according to a 2010 study in the Public Library of Science ONE (PLoS One).  After reviewing data from the U.S. Food and Drug Administration’s adverse event reporting system, the authors of the study concluded that 31 drugs were disproportionately associated with violent thoughts and actions – including homicide.  These 31 drugs accounted for 79% of all the reports of violence the FDA received from 2004 through September 2009.

Sertraline, marketed under various names including Zoloft, is a drug in the newer class of antidepressants known as SSRIs (selective serotonin uptake reinhibitors).  To date, 34 studies and 26 warnings issued by international drug regulatory authorities have warned about the dangers of sertraline and other SSRI antidepressants.  The very long list of dangerous side effects include abnormal behavior, emotional changes, suicide, anxiety, agitation, aggression and violence.

Clonazepam, marketed as Klonopin, is a DEA schedule IV controlled substance in the class of addictive drugs known as benzodiazepines, which the U.S. Drug Enforcement Administration (DEA) warns can cause hostility.  The Canadian national public health department, Health Canada, warns that clonazepam can cause hallucinations and delusional thinking.

The next two meetings between Fenton and Holmes were short “meds checks.”  Fenton discontinued the clonazepam when Holmes reported it was ineffective.  She recommended another antipsychotic drug, quetiapine, marketed as Seroquel.

Quetiapine (Seroquel) is also on the PLoS One’s list of the 31drugs most associated with violence.

Holmes declined to take Seroquel.

Psychiatrist testifies: “No indication of any threat from him”

In her meetings with Holmes, Fenton asked him to tell her more about his obsessive thoughts of killing people, according to her testimony in court, but he withheld any further information, saying he “won’t give details” or refusing to give any answer at all.

He did admit to her that he hated people.  Fenton testified that in one meeting, Holmes emphasized he wouldn’t hurt himself, but she said that he left her with the impression he could hurt others.

Holmes told her that he “had read Nietzsche, Kaczynski, and the Tylenol terrorist.”  Nietzsche was a German philosopher whose rejection of any universal moral law was summarized in his statement “God is dead.”  Ted Kaczynski is the serial killer known as the Unabomber.  The so-called Tylenol terrorist caused deaths through drug tampering.

Still, Fenton apparently believed him when he said he had no specific plans for killing and no specific targets in mind.  She testified that there was “no indication of any threat from him.”  She saw no change in his demeanor during the months she met with him, testifying that there was “no difference in presentment” between their first and last meetings.

Meanwhile, Holmes’s notebook shows that during the time he was meeting with Fenton, he was actively formulating elaborate plans for mass murder.  He acquired weapons, explosives, and other equipment to carry it out.  He practiced shooting at a target range.

Fenton testified that at her final meeting with Holmes on June 11, she “still had significant concerns about his homicidal thoughts and dangerousness.”  But she also testified that she “thought he was functioning well” and that his plans for his life after dropping out of graduate school “made sense.”

After their final meeting, Fenton never called or followed up with Holmes.

Five weeks later on July 19, Holmes suited up in body armor, armed himself with weapons, a gas canister and gas mask, and set out to commit mass murder.  He also left his apartment booby-trapped with explosives in an attempt to cause even more fatalities.

Holmes sent his notebook to psychiatrist to educate her

Entries in his notebook show contempt for Fenton and another psychiatrist, Robert Feinstein, whom Fenton brought into two of the five meetings she had with Holmes.  He referred to the psychiatrists as “mind rapists.”

After writing that he intended to “deflect incriminating questions” from the psychiatrists about his thoughts of killing, he indicated they made that easy, noting: “Oddly, they don’t pursue or delve farther into harmful omissions.”

He challenged Fenton in one meeting, asking her “Are you just a pill pusher?”

Holmes mailed his notebook to Fenton just hours before his deadly attack on the theater.  In an interview two years later, Holmes said he mailed the notebook to Fenton to educate her so that “something like this wouldn’t happen again.”

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News for Colorado

Columbine: A Permanent Reminder That Psychiatric Drugs Can Turn Kids Into Killers

The 13th anniversary of the shooting rampage at Columbine High School in Littleton, Colorado, is a time to remember the real lesson of Columbine: psychiatric drugs can turn kids into killers.

 Shooter Eric Harris was taking the antidepressant Luvox at the time he and Dylan Klebold opened fire at Columbine High School, killing 12 students and a teacher and wounding 26 others before killing themselves.

There is at least one public report that Klebold had also been taking antidepressants.  A friend of Klebold claims she witnessed him taking the antidepressants Paxil and Zoloft and urged him to come off them.  Officially, Klebold’s medical records remain sealed.

Luvox, Paxil and Zoloft are in a class of drugs called selective serotonin reuptake inhibitors (SSRIs).  The FDA is among the international regulatory agencies issuing warnings on SSRIs.  Its Public Health Advisory issued in 2004 warned:

“Anxiety, agitation, panic attacks, insomnia, irritability, hostility, impulsivity, akathisia [severe restlessness], hypomania [abnormal excitement, mild mania] and mania [psychosis characterized by exalted feelings, delusions of grandeur and overproduction of ideas] have been reported in adult and pediatric patients being treated with antidepressants.”

International studies and warnings about antidepressants can be accessed through CCHR International’s psychiatric drug side effects search engine.

Psych Dugs Dominate List of 10 Most Violence-Inducing Drugs

Luvox, Paxil and other antidepressants are ranked among the top 10 most violence-inducing prescription drugs in a list compiled by the Institute for Safe Medication Practices.  The list is based on data from the FDA’s Adverse Event Reporting System.

Dr. Ann Blake Tracy, executive director of the International Coalition for Drug Awareness and author of Prozac: Panacea of Pandora? – Our Serotonin Nightmare, is an expert consultant in cases like Columbine in which antidepressants are involved.  Dr. Tracy say the Columbine killers’ brains were awash in serotonin, the chemical which causes violence and aggression and triggers a sleep-walking disorder in which a person literally acts out their worst nightmare.

Harris became obsessed with homicidal and suicidal thoughts “within weeks” after he began taking Zoloft, according to Dr. Tracy.  Due to his obsession with killing, Harris was switched to Luvox, which was in his system at the time of the shooting, according to his autopsy.

But the change from Zoloft to Luvox is no more of a change than switching from Pepsi to Coke, Dr. Tracy said.  The change did not avert the Columbine tragedy, and antidepressants are directly and forever linked to it.

WARNING:  Anyone wishing to discontinue psychiatric drugs is cautioned to do so only under the supervision of a competent medical doctor because of the risk of dangerous, even life-threatening withdrawal symptoms.

If you or someone you know has experienced the harmful effects of psychiatric drugs (including violence), we want to talk to you.  You can contact us privately by clicking here or by calling 303-789-5225.  All information will be kept in the strictest confidence.  We welcome your comments on this article below.

 

 

 

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Killers On Psych Drugs News for Colorado

Parker Man Who Killed Ex-Wife, Then Committed Suicide Had Taken Psych Drug

 

Image by Raki Halder
Image by Raki Halder

A man who shot and killed his ex-wife outside a McDonald’s in Parker last December and then took his own life had taken the antidepressant nortriptyline, according to an autopsy report.

Royer reportedly was having emotional and financial problems at the time of the double killing.  So how does a depressed individual turn violent?

Antidepressants have long been linked to violence.  Nortriptyline is known to cause hostility, aggression, agitation, confusion, hallucinations and delusions.

It also can cause worsening depression, suicidal thoughts, suicide attempts and suicide.

Research studies, warnings from international regulatory authorities, and reports to the U.S. Food and Drug Administration on the harmful side effects of antidepressants and other psych drugs can be accessed through CCHR International’s psychiatric drug side effects search engine.

WARNING: Anyone wishing to discontinue antidepressants or other psychiatric drugs is cautioned to do so only under the supervision of a competent medical doctor because of potentially dangerous withdrawal symptoms.

If you or someone you know has experienced harmful side effects from an antidepressant drug, we want to talk to you. You can contact us privately by clicking here or by calling 303-789-5225. All information will be kept in the strictest confidence. We welcome your comments on this article below.

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General News

Chance of Autism Doubles with Antidepressant Use During Pregnancy

A study just published in the Archives of General Psychiatry found that the odds of having an autistic child doubled for mothers who took newer antidepressants known as SSRIs (selective serotonin reuptake inhibitors) during the year before delivery.

SSRIs include Prozac, Zoloft, Celexa and Lexapro, among others.

The study found that the rate was greater than two autistic children per 100 mothers on SSRIs, with the rate higher still if mothers took SSRIs in the first trimester of their pregnancy.

The research was undertaken because the rising incidence of autism in recent years parallels a rise in the use of SSRIs during pregnancy.

A second study just released also suggests that environmental factors, including prenatal conditions, play a significantly larger role in autism.

Dr. Joseph Coyle, editor-in-chief of the psychiatry journal, called the two studies “game changers.”

Clara Lajonchere, an author of one of the studies and vice president of clinical programs for the research and advocacy organization Autism Speaks, said that “much more emphasis is going to be put on looking at prenatal and perinatal [around the time of childbirth] factors with respect to autism susceptibility.”

Pregnant women currently taking SSRIs are cautioned against suddenly discontinuing them.  No one should stop taking any psychiatric drug without the advice and supervision of a competent medical doctor.

If you or someone you know gave birth to a child with birth defects or other problems after taking psychiatric drugs during pregnancy, we want to talk to you.  You can contact us privately by clicking here or by calling 303-789-5225.  All information will be kept in the strictest confidence.  We welcome your comments on this article below.

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Killers On Psych Drugs News for Colorado

The Real Lesson of Columbine: Psychiatric Drugs Induce Violence

Filmmaker Michael Moore Weighs In On Why Columbine Happened

On this 12-year anniversary of the shooting rampage at Columbine High School in Littleton, Colorado, let us not forget the real lesson of Columbine:  psychiatric drugs induce violence.

Shooter Eric Harris was taking the antidepressant Luvox at the time he and Dylan Klebold opened fire at Columbine High School, killing 12 students and a teacher and wounding 26 others before killing themselves.  At least one public report exists of a friend of Klebold who witnessed Klebold taking the antidepressants Paxil and Zoloft and urged him to come off them.  Officially, Klebold’s medical records remain sealed.

Luvox, Paxil and Zoloft are in a class of drugs called selective serotonin reuptake inhibitors (SSRIs).  Among the international regulatory agencies issuing warnings on these antidepressants, the FDA issued a Public Health Advisory in 2004 warning that “anxiety, agitation, panic attacks, insomnia, irritability, hostility, impulsivity, akathisia [severe restlessness], hypomania [abnormal excitement] and mania [psychosis characterized by exalted feelings, delusions of grandeur and overproduction of ideas] have been reported in adult and pediatric patients being treated with antidepressants.”  (For further information on international studies and warnings about antidepressants, go to CCHR International’s psychiatric drug side effects search engine.)

Luvox, Paxil and other antidepressants also made the top 10 list of violence-inducing prescription drugs in a report from the Institute for Safe Medication Practices, which was based on data from the FDA’s Adverse Event Reporting System (see “Study Reveals Top Ten Violence-Inducing Prescription Drugs [– Eight Are Psychiatric Drugs]”).

Dr. Ann Blake Tracy, executive director of the International Coalition for Drug Awareness and author of Prozac: Panacea or Pandora? – Our Serotonin Nightmare, is an expert consultant in cases like Columbine in which antidepressants are involved.

Dr. Tracy says the Columbine killers’ brains were awash in serotonin, the chemical which causes violence and aggression and triggers a sleep-walking disorder in which a person literally acts out their worst nightmare.  Harris became obsessed with homicidal and suicidal thoughts “within weeks” after he began taking Zoloft, according to Dr. Tracy.  Due to his obsession with killing, Harris was switched to Luvox, which was in his system at the time of the shooting, according to his autopsy. However, the change from Zoloft to Luvox is like switching from Pepsi to Coke, Dr. Tracy said.

A growing number of school shootings and other shooting rampages were committed by individuals under the influence of, or in withdrawal from, psychiatric drugs known to cause mania, psychosis, violence and even homicide. Consider this list of 13 massacres over the past decade or so, resulting in 54 dead and 105 wounded – and these are just the ones where the psychiatric drugs are known. In other cases, medical records were sealed or autopsy reports not made public or, in some cases, toxicology tests were either not done to test for psychiatric drugs or not disclosed to the public. But this is what we do know about the mental health “treatment” of those who committed these acts of violence:

  • Dekalb, Illinois – February 14, 2008: 27-year-old Steven Kazmierczak shot and killed five people and wounded 16 others before killing himself in a Northern Illinois University auditorium. According to his girlfriend, he had recently been taking Prozac, Xanax and Ambien. Toxicology results showed that he still had trace amount of Xanax in his system.
  • Omaha, Nebraska – December 5, 2007: 19-year-old Robert Hawkins killed eight people and wounded five before committing suicide in an Omaha mall. Hawkins’ friend told CNN that the gunman was on antidepressants, and autopsy results confirmed he was under the influence of the “anti-anxiety” drug Valium.
  • Jokela, Finland – November 7, 2007: 18-year-old Finnish gunman Pekka-Eric Auvinen had been taking antidepressants before he killed eight people and wounded a dozen more at Jokela High School in southern Finland, then committed suicide.
  • Cleveland, Ohio – October 10, 2007: 14-year-old Asa Coon stormed through his school with a gun in each hand, shooting and wounding four before taking his own life. Court records show Coon had been placed on the antidepressant Trazodone.
  • Blacksburg, Virginia – April 16, 2007: 23-year-old Seung Hui Cho shot to death 32 students and faculty of Virginia Tech, wounding 17 more, and then killing himself. He had received prior mental health treatment, however his mental health records remained sealed.
  • Red Lake, Minnesota – March 2005: 16-year-old Jeff Weise, on Prozac, shot and killed his grandparents, then went to his school on the Red Lake Indian Reservation where he shot dead 7 students and a teacher, and wounded 7 before killing himself.
  • Greenbush, New York – February 2004: 16-year-old Jon Romano strolled into his high school in east Greenbush and opened fire with a shotgun. Special education teacher Michael Bennett was hit in the leg. Romano had been taking “medication for depression”.
  • El Cajon, California – March 22, 2001: 18-year-old Jason Hoffman, on the antidepressants Celexa and Effexor, opened fire on his classmates, wounding three students and two teachers at Granite Hills High School.
  • Williamsport, Pennsylvania – March 7, 2001: 14-year-old Elizabeth Bush was taking the antidepressant Prozac when she shot at fellow students, wounding one.
  • Conyers, Georgia – May 20, 1999: 15-year-old T.J. Solomon was being treated with antidepressants when he opened fire on and wounded six of his classmates.
  • Columbine, Colorado – April 20, 1999: 18-year-old Eric Harris and his accomplice, Dylan Klebold, killed 12 students and a teacher and wounded 26 others before killing themselves. Harris was on the antidepressant Luvox. Klebold’s medical records remain sealed.
  • Notus, Idaho – April 16, 1999: 15-year-old Shawn Cooper fired two shotgun rounds in his school, narrowly missing students. He was taking a prescribed SSRI antidepressant and Ritalin.
  • Springfield, Oregon – May 21, 1998: 15-year-old Kip Kinkel murdered his parents and then proceeded to school where he opened fire on students in the cafeteria, killing two and wounding 22. Kinkel had been taking the antidepressant Prozac.

Filmmaker Michael Moore, who directed the documentary “Bowling for Columbine,” has said this, following his extensive look at the Columbine tragedy:

“In Bowling for Columbine,” we never really came up with the answer in terms of why this happened. I think we did a good job of exposing [that] all the reasons that were given were a bunch of B.S. ….And none of it really made any sense. That’s why I believe there should be an investigation in terms of what…prescribed pharmaceuticals these kids were on….

“It just would be shocking…to the millions of parents who prescribe this for their kids if it was finally explained to them, if this is the case, that this perhaps occurred for no other reason other than because of these prescriptions. “Imagine what that would do, imagine how people would totally re-think things – grasping for every little straw they can to explain why something like Columbine happens, when in fact it may be nothing more than this. How else do you explain two otherwise decent kids, very smart, no history of violence to other kids in the school – why them, why did this happen? It’s an extremely legitimate question to pose, and it demands an investigation.” (See the video clip of Michael Moore here.)

Given the growing list of shooters who were on psychiatric drugs, given the fact that 22 international drug regulatory agencies warn these drugs can cause violence, mania, psychosis, suicide and even homicide, and given the fact that a major study was just released confirming these drugs put people at greater risk of becoming violent, CCHR International asserts:  “Any recommendation for more mental health ‘treatment,’ which [inevitably] means putting more people and more kids on these [psychiatric] drugs, is not only negligent, but considering the possible repercussions, criminal.”

If you or someone you know has been harmed by psychiatric drugs, you can contact us privately by clicking here or by calling 303-789-5225.  All information will be kept in the strictest confidence.   We welcome your comments on this article below.

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